HPA Adapt


HPA Adapt support stress hormone balance via the HPA Axis with adaptogenic herbs.

  • Non-stimulant formula.
  • Reduces mental stress and fatigue.
  • Supports mood and calms occasional anxiety.
  • Supports cognitive function.

 Soy Free Product



HPA Adapt combines five powerful adaptogenic herbs to help the body better respond to both mental and physical stressors.

Supports healthy stress hormone balance via the HPA axis.
  1. Key ingredients such as Rhodiola root extract, Sensoril, Ashwagandha, and Eleuthero root extract, combined with standardized extract of Maca and Holy Basil leaf.
  2. The hypothalamic-pituitary-adrenal axis, or HPA axis, is the central part of the stress response system.
  3. It involves a complex set of interactions and feedback loops between the hypothalamus, the pituitary, and the adrenal glands.
  4. The HPA axis also plays a role in the regulation of other systems of the body, including the gastrointestinal, neurological, and immune systems.
  5. Therefore, supporting optimal HPA axis function is important to maintaining overall health and wellness.
HPA Adapt can be taken in conjunction with Cortisol Manager when additional energy, and stress support is needed.
Clinician Curated

Our supplements are curated by clinicians, based on established ingredient studies, and formulated to include ingredients at relevant levels of dosing.

Premium Ingredients

Developing products that you can count on begins at the source. We work exclusively with partners who share our rigor for quality, choosing ingredients that meet stringent requirements for maximum benefit.

Trusted Products

We have built quality into every aspect of our business — from our facility to our processes, to our people. We create products you can trust — batch to batch, bottle to bottle, and capsule to capsule.


Q. Why is HPA Adapt not recommended for pregnant women?
A. HPA Adapt is not recommended for pregnant women because it includes Holy Basil. The Natural Standard states that “Based on traditional use, holy basil should be avoided during pregnancy, due to its ability to stimulate uterine contractions.” 1 References1. Ahmed M et al. Effects of Ocimum sanctum (Tulsi) on the reproductive system: An updated review. Biomedical Research 2002;. 13 (2/3): 63-67.)

Q. Are there any drug-nutrient interactions with HPA Adapt?
A. Caution should be taken whenever recommending, or consuming, nutritional supplements. Healthcare professionals can use this drug-nutrient interaction checker to view potential interactions with the ingredients of HPA Adapt. Patients should consult their preferred healthcare professional for any supplement questions.

Serving Size: 4 capsules
Total Carbohydrate <1 g <1%†
Rhodiola (Rhodiola rosea) Root Extract standardized to contain 3% rosavins and 1% salidroside 400 mg**
Ashwagandha (Withania somnifera) (Sensoril® brand) Root and Leaf Extract 300 mg**
Eleuthero (Eleutherococcus senticosus) Root Extract standardized to contain 0.8% eleutherosides 300 mg**
Holy Basil (Ocimum sanctum) Leaf Extract standardized to contain 2.5% triterpenoic acids including ursolic and oleanolic acids 200 mg**
MacaPure® brand Maca (Lepidium meyenii) Root Extract standardized to contain 0.6% macaenes and macamides 150 mg**
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HPA Adapt

HPA Adapt