Phosphatidylserine Benefits, Uses, Side Effects, and More

December 18, 2022

What is Phosphatidylserine?

Phosphatidylserine is a fatty component known as a phospholipid; it acts as a protective barrier to your brain’s cells while also carrying signals between them. Phosphatidylserine is essential for cognitive health, mental stability, and memory sharpness.

Phosphatidylserine is essential for healthy nerve cell membranes; human brain aging is associated with biochemical changes and structural degradation that affect neurotransmission; several studies find that it may improve cognitive abilities. People who took the supplement performed better on tests of short-term memory, mood, attention, and recall of names.

Does Phosphatidylserine Improve Memory Function?

Clinical trials of oral phosphatidylserine in humans showed cognitive enhancement results, measured by electro-encephalography of subjects receiving 300 mg of phosphatidylserine, including 37.5 mg of DHA and EPA omega 3 fatty acids for 42 days resulting in a relaxed state and ability to recall words increased by 42% in both genders older than 60 years of age who complained of memory disorder without adverse effects at the given dose.

Phosphatidylserine supplementation is well absorbed in humans, penetrates the blood-brain barrier, and safely slows, stops, or reverses biochemical changes and structural degeneration in nerve cells.

Phosphatidylserine supports human cognitive functions such as short-term memory formation, long-term memory support preservation, the ability to regain memories, recall information, remain focused and concentrate, solve problems, language skills, and communication in addition to improving locomotor activities (quick responses and reflexes).

Phosphatidylserine for Anxiety

Clinical trials showed that in chronically stressed subjects, Phosphatidylserine can be effective is stress relive by normalizing cortisol responses through the hypothalamic-pituitary-adrenal axis.

Cortisol influences several physiological functions, including glucose, lipid, and protein metabolism, immune system function, and energy supply to the nervous system.

Chronic psychological stress has been demonstrated to cause hypothalamic-pituitary-adrenal dysregulations, which contribute to impaired psychological well-being.

Phosphatidylserine Benefits

  • Phosphatidylserine is taken to slow memory loss progression and mental deterioration as we age.
  • Boost cognitive function.
  • Management of Alzheimer’s disease symptoms.
  • Recovery of athletes who experience muscle discomfort and stress.

Phosphatidylserine for

Possible Side Effects of Phosphatidylserine

At doses of 300 mg and higher, side effects are more common and could include:

  • Difficulty sleeping.
  • Stomach discomfort.
  • Bloating.

Daily Dose of Phosphatidylserine

  1. Cognitive/Memory Impairment 100 mg/Three times a day.
  2. Alzheimer’s Disease 100 mg/Three times a day.
  3. ADHD in Children 200-300 mg/One a day.

Safety of Phosphatidylserine

When taken for up to three months, phosphatidylserine is safe. Side effects of phosphatidylserine include insomnia and stomach distress, especially at dosages of more than 300 mg.
Products derived from animals can spread illnesses such as mad cow disease; there have been no reports of people developing animal illnesses from phosphatidylserine supplements; look for plant-based supplements.

Best Phosphatidylserine Supplement for Cognitive Health

Cognition refers to using your brain in a wide range of sophisticated brain processes (cognitive functions), such as attention, memory, processing speed, and mental functions (problem-solving, multitasking, reasoning and planning).


Daily Dose of Phosphatidylserine 1

Maximum cognitive health is achieved by relying on a blend of potent ingredients, not just one, to strengthen the body’s stress response and resilience through both short and long periods of stress.

IQ Adapt

  • Phosphatidylserine (from Sunflower seed) 100 mg
  • Bacopa Extract 300 mg
  • Ashwagandha Root Extract 250 mg
  • Eleuthero Root Extract 200 mg
  • L-Theanine (Suntheanine) 100 mg

The unique formulation of adaptogenic botanicals and nutrients is designed to boost fatigue resistance, memory enhancement and maintenance of balanced cortisol and DHEA levels.

IQ Adapt


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