Neurological and Cognitive Health

Synapsin is a component ingredient powder blend of ginsenoside Rg3 and nicotinamide riboside used in a nasal spray for neurological and cognitive health.

Synapsin was invented by renowned author, pharmacist and functional medicine speaker Jim LaValle, RPh, CCN, ND, and is commonly used as a component ingredient in nonsterile methylcobalamin or hydroxocobalamin formulations to support neuronal function and cognition.†

  • Fights inflammation, empowers Boosts neurons,and gets the mitochondria to calm down the microglia.
  • Helps mitochondria to become fully active and generate energy in the brain.
  • helps with sirtuins (SIRT1’s) which are regulators of metabolism.
Methylcobalamin (RG3-Synapsin®) Nasal Spray

About Ginsenoside Rg3

Rg3 is one of several triterpene saponins (ginsenosides) found in the plant genus Panax, including Panax ginseng (Asian ginseng) and Panax quinquifolius (American ginseng). Laboratory studies report that Rg3 extracted from Panax ginseng supports neuroprotection, helping to support healthy microglial activity  and healthy neuronal function.1,2,3

About Nicotinamide Riboside

Nicotinamide riboside (NR) is a form of vitamin B3 found in cow’s milk. 4 Laboratory studies report administration of nicotinamide riboside supports healthy levels of NAD+ in yeast and cultured human and mammalian cells. NR is reported to be incorporated into the cellular NAD+ pool via the action of nicotinamide riboside kinase (Nrk) pathway or via nicotinamide (Nam) salvage after conversion to Nam by phosphorolysis.4,5,6 † Laboratory studies have also reported the supportive and neuroprotective role for NAD +.5† In laboratory studies, nicotinamide riboside supports neuronal NAD+ synthesis without inhibiting sirtuins, which are important regulators of metabolism and longevity.7,8†


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 Statements made are for educational purposes and have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Methylcobalamin (RG3-Synapsin®) Nasal Spray
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