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1 fl oz

AGE-DEFIANCE SERUM supports the stimulation of collagen production and revitalizes the flow of oxygen, hydration, and nutrients to your skin cells.

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This pioneering skincare product combines the Nobel Prize-winning discovery of Nitric Oxide with 20% Vitamin C to defy the signs of skin aging. N1o1 supports the stimulation of collagen production and revitalizes the flow of oxygen, hydration, and nutrients to your skin cells.

As we age, Nitric Oxide production decreases, contributing to skin aging. N1o1 helps replenish Nitric Oxide levels, directly combating the root causes of skin aging—wrinkles, dark spots, fine lines, and loss of tone and texture.

Backed by 20 years of research and proven effective in four clinical studies, our unique patent-pending formula generates Nitric Oxide molecules visible working on the skin within seconds. With regular use, most notice the disappearance of wrinkles, reduced pore size, improved skin tone and texture, increased clarity, and reduction in dark spots.

N1o1 Anti-Aging Serum—defy aging, and rediscover youthful, radiant skin. 

  • Innovative Nitric Oxide Serum: Brought to you by Dr. Nathan S. Bryan, our groundbreaking N1o1 face serum, supported by numerous clinical trials, may dramatically reduce the appearance of wrinkles in under a month, enhance skin elasticity, and smoothen your complexion. It’s the FIRST skincare solution that uses Nitric Oxide, a Nobel Prize-winning discovery, to directly tackle the cause of aging skin.
  • Potent Anti-Aging Benefits: The N1o1 serum supports collagen production and replenishes the flow of oxygen, hydration, and essential nutrients to your skin cells. This powerhouse formula works to reduce wrinkles, and fine lines and may support significantly improved skin tone & texture.
  • Nobel Prize-Winning Innovation: Our N1o1 Anti-Aging Serum is an innovative skincare solution that harnesses the power of Nitric Oxide, a Nobel-Prize-winning molecule by addressing the underlying causes of skin aging at a cellular level, such as wrinkles, collagen loss, and dehydration.
  • Effortless Skincare Routine: Our serum is simple to use. Each bottle delivers up to 70 applications. Mix a single pump from each chamber in your palm and apply it to your face and neck. Allow 1-2 minutes for full absorption before using other facial products. Use both morning and night for optimal results.
  • Proven Results: Supports the disappearance of wrinkles, and dark spots, and the improvement of skin tone with regular use. Your skin will not look healthier and feel more youthful! Our formula’s effectiveness is backed by 20 years of research and confirmed in four Clinical Studies.

Suggested use



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