Understanding Testosterone: How It Protects Breasts & Muscles.

June 13, 2023

Introduction:-

Nature always operates with purpose and reason. Interestingly, testosterone (male sexual hormone), is the most abundant biologically active hormone in women, It plays a significant role in our bodies. It’s worth noting that male androgen receptors (AR) are present throughout the female body, including in breast tissue, where testosterone actually helps reduce tissue growth.

What is Cancer:-

Cancer, as we all know, is a condition characterized by uncontrolled growth. It’s a fear we all share. Cancer cells have the ability to outlive us and become immortal. However, our bodies have mechanisms to keep this growth in check and protect our breast tissue. These natural “growth controllers” play a vital role in preventing cancer and maintaining the safety of our breast and prostate tissue.

What is Cancer

How testosterone levels affect breast tissue:-

Let’s explore the role of testosterone further. Within our bodies, testosterone naturally breaks down into DHT and then into a compound called 3-beta diol. Interestingly, 3-beta diol has a similar structure to a protective anti-cancer estrogen called estriol, as well as breast-protective isoflavones. Recent clinical data support the idea that testosterone plays a role in preventing and treating breast cancer. For instance, women with hormone deficiency symptoms who received pharmacological doses of testosterone, either alone or in combination with anastrozole, experienced a reduced incidence of breast cancer.
Moreover, combining testosterone with anastrozole effectively treated hormone deficiency symptoms in breast cancer survivors without causing a recurrence. It’s worth noting that implants containing testosterone and anastrozole placed near malignant tumors in breast tissue significantly reduced the size of the tumors. These findings further demonstrate the direct anti-proliferative, protective, and therapeutic effects of testosterone.

In addition to testosterone, some doctors consider melatonin or grape seed extract as natural aromatase inhibitors to prevent estrogen conversion. These potential treatments emphasize the importance of maintaining hormonal balance and protecting breast tissue. Experimental studies have shown that testosterone acts against cancer by inhibiting cell proliferation and promoting cell death. Animal studies suggest that testosterone may serve as a natural protector of the breast, limiting the cancer-promoting effects of estrogen on the mammary epithelium. Notably, in premenopausal women, higher testosterone levels are not associated with a greater risk of breast cancer.
Similarly, women with polycystic ovary syndrome, who have chronically elevated estrogen exposure and excess androgen levels, do not face an increased risk of breast cancer. However, postmenopausal women with low estrogen levels and increased fat tissue aromatase activity may experience an increased risk of breast cancer with higher testosterone levels. Therefore, it is crucial to discuss the addition of testosterone to hormone replacement therapy (HRT) with your healthcare provider.

Testosterone’s Role in Fitness and Strength:-

Beyond its potential role in breast cancer prevention, testosterone also helps protect muscle mass. Muscles play a vital role in slowing the aging process, and testosterone contributes to boosting metabolism and maintaining a leaner physique.
However, it is important to find a balance. Excessive levels of testosterone can have negative effects on the heart, skin, and mood. A knowledgeable healthcare professional will explain the positives and negatives of different hormonal therapies and help determine the ideal hormonal balance for each individual. It’s important to recognize that hormonal needs may change over time due to aging or other life circumstances.

Conclusion:-

To sum up, testosterone is a hormone that plays a significant role in maintaining hormonal balance and protecting against breast cancer. It is important to consult with a healthcare professional to understand its potential benefits and risks and find the most suitable hormonal balance for your specific needs.

Conclusion

Resources:-

  1. Testosterone and Breast cancer prevention
  2. Rapid response of breast cancer to neoadjuvant intramammary testosterone-anastrozole therapy: neoadjuvant hormone therapy in breast cancer
Categories: Compounding